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Latest news in the field of chromatography column manufacturing technologies

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After the Pittcon World Conference in Philadelphia, USA in 2022, many chromatography equipments have been introduced and offered to the global market in mass production. Every year, these equipments are introduced to the world in order to upgrade the separation and analysis systems, to improve the performance of the identification and analysis systems and to make the results of chemical analysis more accurate than ever before. We will briefly mention a few of the achievements of leading companies in the field of separation systems:

Chromanik Technology has unveiled its latest breakthrough in the field of chromatography columns, the Sunsheel C18 chromatography column, which is based on a 3.5µm (90Å) SPP surface with a unique end-capping process using high temperature and the end-capping agent hexamethyldichlorotrisiloxane, along with the Sunniest PFP C18&PFP column, which is a mixture of pentafluorophenylpropyl and octadecyl phases built on a (5µm, 120Å) substrate. These columns have been introduced with the ability to operate in a wider pH range and a more hydrophobic phase for the separation of small molecules.

Advanced Material Technology has introduced the Halo 1.5 series of columns for small molecules, peptides and proteins using 2.7µmSPP 2.0-technology. The 1.5mm ID columns provide greater sensitivity than traditional UHPLC systems, higher throughput in LC-MS systems and higher throughput than 1mm ID columns in UHPLC systems, while reducing solvent consumption by 50% (compared to 2.1mm ID). According to the company, this is a simple microflow solution and the columns are available in a variety of surface chemistries for small molecules.

Fortis has introduced a new line of columns (Evosphere) based on a single, uniform FPP architecture. These columns offer significantly higher efficiency due to their compactness while maintaining a high loading capacity. According to the company, this approach is an alternative to using SPP-based phases for improved efficiency. The new line is based on a 100 Å pore size and is available in particle sizes of 1.7, 3 and 5 μm. Several surface chemistries are available, such as C18 AR (mixed C18 and aromatic coupling), C18/PFP, diphenyl, phenyl-hexyl, AQUA, C12, RP18-amide and PFP.

Waters has introduced a new series of passivated metal-coated chromatography columns with MaxPeak high-performance surface technology. All of these new columns are designated Premier. The series of columns (hybrid particles 1.7 and 2.5 μm, 130 Å), C8, phenyl and (HILIC) phases (without BEH particles) have been developed. C8 is described as a less inhibitory phase than standard C18 phases and has high pH stability. The phenyl phase offers greater selectivity than C18 phases, especially for polyaromatic compounds, and has high pH stability like C8. The HILIC phase also shows pH stability and is used for highly polar compounds. The Premier series of columns offers a C18 phase and a PFP phase. These columns are built on 1.8 and 2.5 µm PFP particles with a pore size of 100Å and have high coverage. The C18 series offers high retention and exceptional peak shape for bases, while PFP provides greater selectivity than C18 and separation of closely related compounds with sharp peaks for bases.

Large companies such as Shimadzu, Thermo, etc. also launched new products, information on all of which is available on the website below.

For more information, visit the news source chromatographyonline.com

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